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Hernandez Research Group
  • Personnel
  • Recent/Selected Publications
  • Research
  • Outreach and Education
  • Social
  • Media

Recent/Selected Publications

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Biomechanics and Mechanobiology of Bacteria

  • Lee, J., Jha, K., Harper, C.E., Zhang, W., Ramsukh, M., Bouklas, N., Chen, P., Hernandez, C.J. (2023) “Determining the Young’s Modulus of the Bacterial Cell Envelope Using Microfluidic-based Extrusion Loading”. ACS Biomater Sci Eng. 13;10(5):2956–66.
  • *Harper, C.E., *Zhang, W., Shin, J., van Wjingaarden, E., Chou, E., Lee, J., Wang, Z., +Dörr, T., +Chen, P., +Hernandez, C.J. (2023) “Mechanical stimuli activate gene expression for bacterial cell-wall synthesis” Sci Rep 13, 13979. https://doi.org/10.1038/s41598-023-40897-w
  • *Genova, L.A., *Roberts, M.F., Wong,Y-C, Harper, C.E., Santiago, A.G.,Fu, B., Srivastava, A.,Jung, W., Wang, L.M., Krzemiński, L., Mao, X, Sun, X., Hui, C-Y, + Chen, P., +Hernandez, C.J. (2019) “Mechanical stress compromises multicomponent efflux complexes in bacteria” Proc Natl Acad Sci U S A. 116(51):25462-25467. doi: 10.1073/pnas.1909562116.
Microbiome and Musculoskeletal Disease
  • Liu C., Cyphert E.L., Stephen S.J., Wang B., Morales A., Nixon J., Natsoulas N., Garcia M., Carmona PB, Vill A., Donnelly E., Brito I.L., Vashishth D., Hernandez C.J. (2024) “Microbiome-induced Increases and Decreases in Bone Tissue Strength can be Initiated After Skeletal Maturity. J Bone Miner Res. 39(11):1621-1632.
  • Hernandez, C.J., Yang, X., Ji, G., Niu, Y., Sethuraman, A.S., Koressel, J., Shirley, M., Fields, M.W., Chyou, S., Li, T.M., Luna, M., Callahan, R.L., Ross, F.P., Lu, T.T., Brito, I.L., Carli, A.V., Bostrom, M.P.G. (2019) “Disruption of the Gut Microbiome Increases Risk of Periprosthetic Joint Infection in Mice” Clin Orthop Rel Res. 477(11):2588-2598.
  • Guss J.D., Horsfield, M.W., Fontenele, F.F., Sandoval, T.N., Luna, M., Apoorva, F., Lima, S.F., Bicalho, R.C., Singh, A., Ley, R.E., van der Meulen, M.C.H., Goldring, S.R., Hernandez, C.J. (2017) “Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties” J Bone Miner Res. 32(6):1343 1353.
Engineered Living Materials
  • Heveran, C.M., Hernandez, C.J. (2023) “Make Engineered Living Materials Carry Their Weight.” Matter. 6 (11): 3705-3718. https://doi.org/10.1016/j.matt.2023.07.023.
  • van Wijngaarden, E.W., Bratcher, S., Lewis, K.J., Hernandez, C.J. (2023) “Solute Transport in Engineered Living Materials Using Bone-Inspired Microscale Channel Networks” Adv Eng Mater https://doi.org/10.1002/adem.202301032.
Biomechanics of Bone
  • Torres, A.M., Trikanad, A.A., Aubin, C.A., Lambers, F.M., Luna, M., Rimnac, C.M., Zavattieri, P.D., Hernandez, C.J. “Bone-Inspired Microarchitectured Materials with Enhanced Fatigue Life” (2019) Proc Natl Acad Sci USA 116 (49) 24457-24462
  • Hernandez, C.J., van der Meulen, M.C.H. (2017) “Understanding Bone Strength Isn’t Enough” J Bone Miner Res. 32(6):1157-1162.
  • *Torres, A.M., *Matheny, J.B., Keaveny T.M., Taylor, D., Rimnac, C.M., Hernandez, C.J. (2016) “Material Heterogeneity in Cancellous Bone Reduces Permanent Deformations After Mechanical Failure.” Proc Natl Acad Sci U S A. 113(11): 2892-2897.
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